LORETA Current Density Normative Database

Description

3-Dimensional Source Localization and
a LORETA Normative Database: Birth to 82 Years

After the correct version of the Key Institute’s software is installed on the users computer then the Key Institute’s LORETA Viewer can be launched directly from NeuroGuide. See the Key Institute documentation to learn how the cross-spectrum and *.crs file is computed.

3-Dimensional LORETA Normative Database

The LORETA normative database used the Key Institute’s ‘T’ matrix and cross-spectrum equations to compute the cross-spectrum of the EEG from each subject in the NeuroGuide normative database for each 2,394 gray matter pixel. The NeuroGuide software was tested by comparisons to the Key Institute software programs. After log10 transforms of the Key Institute’s current density values, the means and standard deviations of the 2,394 LORETA currents were computed for different age groups from birth to 82 years thus enabling a Z score to be computed for each of the 2,394 gray matter pixels and displayed using the Key Institute’s LORETA Viewer and the Key Institute cross-spectral equations. For further detail see how tests of Gaussian distributions and cross-validations were computed.

Time domain export is also available using NeuroGuide so that individual EEG events can be examined in detail in the time domain as well as to compare source localization in the frequency domain.

Export the digital time series to the Key Institute’s LORETA EEG Cross-Spectra program and verify the equivalence of the Key Institute LORETA Explorer for EEG Cross-Spectra to the same data computed by NeuroGuide.