swBrainSurfer is a Brain Computer Interface with a real-MRI with 12,270 voxels, 3-D NeuroImaging of Functional Brain Networks and swLORETA of Brodmann Areas in Real-time and Live Z scores of nodes and connections between nodes as measured by the connectivity of swLORETA Coherence, swLORETA Lagged Coherence, Phase Differences and swLORETA Phase Slope Index (Information Flow).
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The Streamer is a Video Streamer for Neurofeedback. Dock any DVD Player window, or NetFlix, YouTube, hulu or any other Web Service that allows you to watch videos and/or TV show. Currently there are 2 display options available inside the Streamer that you can link to the Reward: Brightness or Size. One must own Surface Z Score Neurofeedback (NF1), LORETA Z Score Neurofeedback (NF2), Surface Cross Frequency Z Score Neurofeedback (NF3) and/or swLORETA Neurofeedback (swNFB) before you can use the ANI Streamer.
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The LORETA Current Density normative database used the Key Institute's 'T' matrix and cross-spectrum equations to compute the cross-spectrum of the EEG from each subject in the NeuroGuide™ normative database for each 2,394 gray matter pixel. The NeuroGuide™ software was tested by comparisons to the Key Institute software programs. After log10 transforms of the Key Institute current density values, the means and standard deviations of the 2,394 LORETA currents were computed for different age groups from birth to 82 years thus enabling a Z score to be computed for each of the 2,394 gray matter pixels and displayed using the Key Institute's LORETA viewer.
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The LORETA Source Correlation Add-on computes the Pearson Product Correlation Coefficient (-1 to +1) with respect to a 3-dimensional Region of Interest (ROI) and the remainder of the 2,394 LORETA Gray Matter Pixels over the time span of selected EEG and then displays the results in the LORETA Viewer. The ROI is identified by either an Anatomical Name or by Brodmann Area. The average current sources of the ROI are used in the computation of the correlation coefficient and the ROI correlation to itself = 0 in the LORETA Viewer.
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LORETA Cross-Frequency Coherence is anEEG LORETA measure of the Coherence (amplitude independent coupling) between frequencies and the center voxels of 88 different Brodmann areas, for example delta and beta or theta and alpha-2 or theta and high beta (Gamma), etc. Neurons in a given Brodmann area communicates with other brain regions over a range of frequencies. This add-on quantifies the coupling and provides a normative database comparison (Z scores) to help link symptoms to dysregulation in the brain.
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The Bi-Spectral analyses includes: Spectrum of the Time Series of Instantaneous Power; Spectrum of the Time Series Relative Power; Spectrum of the Time Series of Instantaneous Coherence; Spectrum of the Time Series of Instantaneous Phase Differences; Spectrum of the Time Series of Instantaneous Amplitude Differences; Spectrum of the Time Series of Phase Reset; and Cross-Frequency Power Correlation (1Hz to 50 Hz).
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Surface Cross-Frequency Power is an EEG measure of the correlation of power between frequencies and scalp locations, for example delta and beta or theta and alpha-2 or theta and high beta (Gamma), etc. A given brain region communicates with other brain region over a range of frequencies. Currently available for Raw Values Only.
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Surface Cross-Frequency Coherence is an EEG measure of the Coherence (amplitude independent coupling) between frequencies and scalp locations, for example delta & beta or theta & alpha-2 or theta & high beta (Gamma), etc. A given brain region communicates with other brain regions over a range of frequencies. This add-on quantifies the coupling and provides a normative database comparison (Z scores) to help link symptoms to dysregulation in the brain.
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The amplitude of higher EEG frequencies (e.g., beta) are related to the phase of lower EEG frequencies (e.g., theta). Therefore, this is a surface EEG measure of the correlation between the phase and amplitude of the EEG across frequencies and scalp locations, for example delta and beta or theta and alpha-2 or theta and high beta (Gamma), etc. This is a unique and important metric that in part reflects the coupling between the upper cortical layers (I-III that generate beta) and the lower cortical layers (V-VI) that generate delta and theta. This add-on quantifies the coupling and provides a normative database comparison (Z scores) to help link symptoms to dysregulation in the brain.
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This powerful new state of the art 3-Dimensional Electrical Neuroimaging tool uses a real-MRI with 12,270 voxels; the Boundary Element Method (to compute the inverse solution to avoid the errors inherent in the use of a spherical head model, allowing for more accurate source localization at depths); and swLORETA (adjusts for source space inhomogeneity and provides accurate estimates of source gradients from the upper to the lower cortical layers). The NeuroNavigator with Raw Current Density values must be purchased before you can have access to the Real-Time NeuroNavigator and the NeuroNavigator Time Domain Capture Tools in NeuroGuide or before purchasing any of the NeuroNavigator add-on options. (See Description Tab).
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Add Functional Connectivity to your NeuroGuide NeuroNavigator, Real-Time NeuroNavigator and the NeuroNavigator Time Domain Capture to view the Raw Scores and/or Z Scores of Coherence, Lagged Coherence and Phase Difference by purchasing the swLORETA Functional Connectivity Normative Database (2 month - 82 years). Must first purchase NeuroNavigator and the swLORETA Current Source Density Normative Database (NNZ) add-on to NeuroGuide™.
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Add Effective Connectivity to your NeuroGuide NeuroNavigator, Real-Time NeuroNavigator and the NeuroNavigator Time Domain Capture to view the Raw and Z Scores of Information Flow (Phase Slope Index) when you purchase the swLORETA Effective Connectivity Normative Database (Birth to 82 years). Must first purchase the NeuroNavigator (NN) and the swLORETA Current Density Normative Database (NNZ) add-ons to NeuroGuide™.
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Add swLORETA Phase Shift & Phase Lock to your NeuroGuide NeuroNavigator, Real-Time NeuroNavigator† and the NeuroNavigator Time Domain Capture to view the Raw Scores and/or Z Scores of Phase Shift and Phase Lock by purchasing the swLORETA Phase Reset Normative Database (2 month - 82 years). Must first purchase NeuroNavigator and the swLORETA Current Source Density Normative Database (NNZ) add-ons to NeuroGuide.
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Add the NeuroNavigator's NaviStat (NNNS) addon to perform Individual and Group Statistics. NaviStat is based on our flagship swLORETA product NeuroNavigator, enhanced with the statistical power of NeuroStat, currently making it the most powerful QEEG comparison program available. NaviStat can compare 2 individual QEEG Conditions or compare changes between 2 groups. With its multi window design the two conditions, along with the resultant comparison can be viewed. One must have the NeuroNavigator before purchasing NaviStat.
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NeuroGuide Acquisition (NGA) is a Stand alone EEG acquisition - useful for Satellite Clinics. Includes collection of EEG, import of .ng, .edf & Text files, re-montage, save and print, marking of traces, color and polarity control of traces. No qEEG or editing capability. Also provides EEG biofeedback capability with purchase of NF1, NF2, NF3, swNF and/or Surfer (see NGA + NF1 and/or NF2 and/or NF3 and/or swNF and/or BrainSurfer). Price is $1,500 for each amplifier system.
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NeuroGuide Acquisition (NGA + NF1) is a Stand alone EEG acquisition - useful for Satellite Clinics. Includes collection of EEG and real-time Surface EEG Biofeedback of Z scores of the Laplacian, Average Reference, Linked Ears, Coherence, Phase Difference, Phase Lock, Phase Shift, Relative Power, Absolute Power with Integrated Symptom Check Lists. No qEEG or editing capability. Does not require the purchase of NeuroGuide. Only one license per purchase is permitted, i.e., a 2nd license requires a 2nd purchase.
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NeuroGuide Acquisition (NGA + NF2) is a Stand alone EEG acquisition - useful for Satellite Clinics. Includes collection of EEG and real-time 3-D LORETA EEG Biofeedback of Z scores of Power, Coherence, Phase Difference, Phase Lock, Phase Shift with Integrated Symptom Check Lists. No qEEG or editing capability. Does not require the purchase of NeuroGuide. Only one license per purchase is permitted, i.e., a 2nd license requires a 2nd purchase.
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NeuroGuide Acquisition (NGA + NF3) is a Stand alone EEG acquisition - useful for Satellite Clinics. Includes collection of EEG and real-time Surface EEG Biofeedback of Z scores of the Laplacian, Average Reference, Linked Ears Phase Difference with Integrated Symptom Checklists. No qEEG or editing capability. Does not require the purchase of NeuroGuide. Only one license per purchase is permitted, i.e., a 2nd license requires a 2nd purchase.
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NeuroGuide Acquisition (NGA + Surf) is a Stand alone EEG acquisition - useful for Satellite Clinics. Includes collection of EEG and a 3-D image of the Brain with real-time Z scores of Power, Coherence, Phase Difference, Phase Lock, Phase Shift with Integrated Symptom Check Lists. No qEEG or editing capability. Does not require the purchase of NeuroGuide. Only one license per purchase is permitted, i.e., a 2nd license requires a 2nd purchase.
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NeuroGuide Acquisition (NGA + swNF) is a Stand alone EEG acquisition - useful for Satellite Clinics. Includes collection of EEG and real-time swLORETA EEG Biofeedback of Z scores of Power, Coherence, Phase Difference, Phase Lock, Phase Shift with Integrated Symptom Checklists that includes 88 Brodmann Areas, plus the Thalamus, Vermis, Red Nucleus and the Cerebellum Regions of Interests. No qEEG or editing capability. Does not require the purchase of NeuroGuide. Only one license per purchase is permitted, i.e., a 2nd license requires a 2nd purchase.
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2 Channel Instantaneous Z Score EEG Biofeedback for Deymed. In 2004 the 1st real-time or "live" Z score controlling biofeedback was distributed as a dynamic link library (DLL) to several companies. Later an Agreement was formed with Deymed for their customer's that wanted to use Deymed's software environment to add Z scores based on the raw values computed in about 1 microsecond or in real-time for 2 channels.
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2, 4 & 19 Channel Instantaneous Z Score EEG Biofeedback. In 2004 Applied Neuroscience, Inc. invented Z score EEG biofeedback. The 1st real-time or "live" Z score controlling biofeedback was distributed as a dynamic link library (DLL) to companies in 2004. Agreements were formed with companies that already had existing scalp surface EEG Biofeedback products using raw EEG data. These companies wanted to use their software environment to add Z scores based on the raw values computed in about 1 microsecond or in real-time for 2, 4 and 19 channels.
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Charge for 1 Replacement or 1 Transfer Key B for any of the Z Score DLLs after the first 2 Transfer B Keys have been issued, with a maximum of one license transfer per year per licensee. Prior to ANI issuing a Transfer or Replacement Key B the Licensee must personally email [email protected] and Certify that the computer has crashed or that the user has removed the DLL from the previous computer and the user must promise not to run the DLL on more than two computers.
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The Expert Mentoring/Consultation services available for Customers and Students that are provided by our ANI Staff includes: Review of Patient EEG Data, Expert Training on NeuroGuide, Training on How to Create Clinical Reports, Special Data Analyses, Advanced Topics. Personal Mentoring Session are provided via TeamViewer or Skype. The Fee is $250/hour
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The e-Book is a "Living" book with 425 figures and tables, including over 275 pages of hands on tutorials. It is a "living" e-Book because it will be updated periodically. The e-Book is organized for beginners and has hyperlinks to allow readers to jump from simple to more complex topics and from the background to the tutorials and from tutorials to scientific detail with a few mouse clicks.